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AUE 8181 - Engine System Analysis, Design and Experimentation Laboratory 0 Credits (2 Contact Hours)
Non-credit laboratory to accompany AUE 8180 . Coreq: AUE 8180 .
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AUE 8190 - Advanced Internal Combustion Engine Concepts 3 Credits (3 Contact Hours)
Examines novel modes of combustion in internal-combustion engines, and provides in-depth study of the underlying phenomena and advanced engine systems required to translate the novel combustion concept into a viable technology. Advanced modeling and simulation tools aid in establishing a link between the fundamentals and system design decisions. Preq: AUE 8160 .
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AUE 8260 - On-Board Vehicle Diagnostics and Reliability 3 Credits (3 Contact Hours)
Discussion of legislated state, federal and international requirements. On-board automotive sensors to monitor vehicle operation and typical diagnostic algorithms are studied. Includes analytical methods for designing fault-tolerant systems and assessing vehicle reliability including safety-critical systems and “limp-home” modes, as well as use of hand-held scanners and specialized diagnostic equipment to classify faults.
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AUE 8270 - Automotive Control Systems Design 3 Credits (3 Contact Hours)
Investigation into derivation of models and design of control strategies for powertrain and chassis control modules and integration into automotive platforms. Also presents software design, sensor selection, system architecture, diagnostics and reliability issues. Application is made to engine management, transmission and chassis systems with a consideration of vehicle performance, safety and information provision. Preq: Graduate standing.
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AUE 8280 - Fundamentals of Vehicle Drivelines and Powertrain Integration 3 Credits (3 Contact Hours)
Study of vehicle powertrain arrangement, manual and automatic transmissions, automotive axles, four-wheel and two-wheel drives and design and manufacturing of gearing systems. Other topics, such as powertrain control to address dynamics in shifting, engine balancing and fuel economy, are addressed. Modeling and computer simulation are used extensively to analyze dynamic performance of various transmissions.
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AUE 8290 - Tire Behavior and Its Influence on Vehicle Performance 3 Credits (3 Contact Hours)
In-depth analysis of the tire and its influence on vehicle performance including design, construction, structural response, rolling resistance, force and moment generation and behavior under dry/wet conditions. Tire models, their limitations and governing equations, tire characteristics on vehicle handling and safety and advanced control concepts in vehicle stability/braking are investigated. Preq: ME 4530.
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AUE 8320 - Vehicle Development and Integration Processes, Methods and Tools 3 Credits (3 Contact Hours)
Overview of the vehicle development process and the tools used in it, including voice of the customer, concept creation, packaging, product specification and target setting, including cost structures, lifecycle product management, prototype development and the role of the supplier. Preq: AUE 8810 .
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AUE 8330 - Automotive Manufacturing Process Development, Methods and Tools 3 Credits (3 Contact Hours)
Overview of automotive manufacturing systems. Issues such as supplier integration, flexible manufacturing, aggregate planning, quality engineering and their applications to manufacturing systems are presented. Emphasizes opportunities and challenges presented with automotive manufacturing in a global environment, integrated processes, product development and automotive supply chain management.
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AUE 8340 - Automotive Production Preparation, Management and Launch 3 Credits (3 Contact Hours)
Effective leadership and management of the product development and launch process. Includes responsibility and role definition, process management tools and software systems, detailed management of the supply chain, performance metrics and cost models and factors affecting launch success. Case studies of historic launch data and improvements are utilized.
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AUE 8350 - Automotive Electronics Integration 3 Credits (3 Contact Hours)
Addresses the integration of electronic components and systems in automotive designs. Provides an overview of the major electronic systems in automobiles and describes how automotive manufacturers specify, integrate and evaluate these systems.
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AUE 8500 - Automotive Stability and Safety Systems 3 Credits (3 Contact Hours)
Discussion of passive/active systems and design philosophies. Investigates stability issues associated with vehicle performance and use of sensors and control system strategies for stability enhancement. Implementation and application to intelligent cruise control, lane departure warning systems, ABS, traction control, active steering systems and vehicle dynamic control systems are also discussed. Preq: ME 4530.
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AUE 8550 - Structural/Thermal Analysis Methods for Automotive Structure, Systems and Components 3 Credits (3 Contact Hours)
Methods to analyze the response of automotive structure, systems and components to static, dynamic and thermal loading. Includes coverage of critical loading conditions and system response objectives. Analysis methods focus on finite element approaches supplemented by simple computational methods when appropriate.
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AUE 8650 - Advanced Composites Manufacturing Processes 3 Credits (2 Contact Hours)
Covers fundamental principles of advanced composites manufacturing processes, including matrix materials, fibers, preforms, processing, extrusion, injection molding, compression molding, filament winding pultrusion, resin transfer molding, liquid infusion techniques, combined with design, environmental issues, process modeling, material removal, assembly, joining, repair, inspection, quality assurance and recycling. Coreq: AUE 8651 .
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AUE 8651 - Advanced Composites Manufacturing Processes Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany AUE 8650 . Coreq: AUE 8650 .
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AUE 8660 - Advanced Materials for Automotive Applications 3 Credits (3 Contact Hours)
In-depth study of the broad range of engineering materials used in the construction of motor vehicles. Considers interrelations between materials microstructure, components manufacturing process and components service behavior. Preq: Consent of instructor.
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AUE 8670 - Vehicle Manufacturing Processes I 3 Credits (3 Contact Hours)
In-depth analysis of main component and subsystem prototyping, fabrication assembly and integration processes used during production of automotive vehicles. Also discusses design for manufacturing, computer-aided manufacturing and rapid tooling technologies. Preq: Consent of instructor.
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AUE 8680 - Vehicle Manufacturing Processes II 3 Credits (3 Contact Hours)
Detailed discussion of OEM-based manufacturing processes in automotive production, including sheet metal stamping, joining, painting and final assembly. Topics covered include the infrastructure, fundamentals of the processes, detailed analysis of the processes and material flow, cost analysis, latest developments, and considerations for various automotive body materials.
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AUE 8690 - Quality Assurance for Automotive Manufacturing Systems 3 Credits (3 Contact Hours)
Overview of manufacturing process control, including evolution of the quality movement, Lean Six Sigma framework, and quality system standards for the automotive industry. In addition to metrology and measurement systems, tools covered include Measurement Systems Analysis, Statistical Quality Control, Advanced Product Quality Planning, and Design of Experiments for manufacturing improvement.
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AUE 8770 - Light-Weight Vehicle Systems Design 3 Credits (3 Contact Hours)
Methodological approaches to weight trade-off during design of vehicle systems, accounting for other functions, cost, safety, materials characteristics and manufacturing constraints. Includes topology optimization, multimaterial approaches and identification of the function optimal materials and material combinations using multi-objective formulations.
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AUE 8800 - Vehicle Design/Manufacture Project Management 3 Credits (3 Contact Hours)
Development of management, leadership, sociocultural and technical skills training for the successful management of an automotive development or research team. Includes problem identification, team dynamics, decision making, ethics, strategy setting, project planning, scope management and implementation, target costing, marketing, design methods and design for X-concepts.
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AUE 8810 - Automotive Systems: An Integrated Overview 3 Credits (3 Contact Hours)
Promotes understanding of the vehicle as a complex system and interactions of its subsystems in terms of performance. Topics include propulsion systems, suspensions and steering systems, tire-road interface, structural behavior and crashworthiness, materials and manufacturing, driver/occupants-vehicle interactions and onboard electronics. Modeling and simulation are used. Coreq: AUE 8811 .
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AUE 8811 - Automotive Systems: An Integrated Overview Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany AUE 8810 . Coreq: AUE 8810 .
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AUE 8820 - Systems Integration Concepts and Methods 3 Credits (2 Contact Hours)
Study of methods and tools to handle functional, geometric, production and IT integration. Includes instruction in managing performance trade-offs from the combination of systems designed for individual functions. Topics also include optimization methods, complexity, validation, signal and IT design and testing methods, robustness, architecture and quality. Coreq: AUE 8821 .
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AUE 8821 - Systems Integration Concepts and Methods Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany AUE 8820 . Coreq: AUE 8820 .
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AUE 8830 - Applied Systems Integration 3 Credits (2 Contact Hours)
Application of integration methods to practical and complex vehicle design and manufacturing systems. Includes prototyping, measurements, tolerancing and validation, as well as diagnosis and sensitivities, methods to diagnose sporadic software errors with hardware in the loop, design reviews, FMEA on function signal, geometry, production. Also includes Fault Tree analysis, innovation and change management, risk analysis and value analysis. Preq: ME 8820 and consent of instructor. Coreq: AUE 8831 .
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AUE 8831 - Applied Systems Integration Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany AUE 8830 . Coreq: AUE 8830 .
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AUE 8850 - Vehicle Layout Engineering and Ergonomic Design 3 Credits (2 Contact Hours)
Study of vehicle layout specifications and considerations related to exterior and interior design. Ergonomics methods and tools as related to occupant accommodation and driver function are presented. Issues of assembly and manufacturing ergonomics are also covered. Case studies are utilized. Coreq: AUE 8851 .
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AUE 8851 - Vehicle Layout Engineering and Ergonomic Design Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany AUE 8850 . Coreq: AUE 8850 .
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AUE 8860 - Vehicle Noise, Vibration and Harshness 3 Credits (3 Contact Hours)
Application of engineering tools and specifications for noise, vibrations and harshness. Sources, mitigation methods, complexity and influences on other vehicle functions are considered. Utilizes design, simulation and validation methods. Preq: Graduate standing.
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AUE 8870 - Methods for Vehicle Testing 3 Credits (2 Contact Hours)
Investigates test planning for various performance regimes, data acquisition and analysis, uncertainty analysis, sensor selection, noise filtering, data reduction methods and track testing methods. Project includes actual vehicle tests. Coreq: AUE 8871 .
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AUE 8871 - Methods for Vehicle Testing Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany AUE 8870 . Coreq: AUE 8870 .
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AUE 8900 - Automotive Engineering Project 1-3 Credits (1-3 Contact Hours)
Industrial project work culminating in writing engineering reports. Projects cover comprehensive analytical and/or experimental treatment of phenomena of current interest in automotive engineering emphasizing modern technological problems. May be repeated for a maximum of nine credits.
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AUE 8920 - Sustainable Vehicle Systems Seminar 1 Credits (1 Contact Hours)
Sustainable vehicle systems seminar.
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AUE 8930 - Selected Topics in Automotive Engineering 3 Credits (3 Contact Hours)
Advanced concepts in multibody systems dynamics including kinematics and kinetics of multibody systems, various methods for equation formulation and their limitations, numerical solutions methods, and applications to automotive systems and subsystems.
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AUE 8950 - External Internship 1-18 Credits (1-18 Contact Hours)
Provides students with an opportunity to apply system integration methods to automotive product and/or process development in an industrial setting.
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AUE 9910 - Doctoral Dissertation Research 1-12 Credits (1-12 Contact Hours)
Doctoral Dissertation Research
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Biochemistry |
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BCHM 6060 - Physiological Chemistry 3 Credits (3 Contact Hours)
Studies chemical basis of the mammalian physiological processes of muscle contraction, nerve function, respiration, kidney function, and blood homeostasis. Discusses composition of specialized tissue such as muscle, nerve, blood, and bone and regulation of water, electrolytes, and acid-base balance. Preq: Consent of instructor.
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BCHM 6230 - Principles of Biochemistry 3 Credits (3 Contact Hours)
Study of the chemistry of amino acids, monosaccharides, fatty acids, purines, pyrimidines, and associated compounds leads to an understanding of their properties and the relationship between structure and function that makes them important in biological processes. The use of modern techniques is stressed. Preq: Consent of instructor.
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BCHM 6310 - Physical Approach to Biochemistry 3 Credits (3 Contact Hours)
Study of chemical and physical properties of amino acids, lipids, nucleic acids, sugars, and their biopolymers. Physical and mathematical analyses are correlated with biological structure and function. Preq: Consent of instructor.
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BCHM 6320 - Biochemistry of Metabolism 3 Credits (3 Contact Hours)
Study of the central pathway of carbohydrate, lipid, and nucleotide metabolism. Emphasizes bioenergetics, limiting reactions, and the regulation and integration of the metabolic pathways. Preq: Consent of instructor.
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BCHM 6330 - General Biochemistry Laboratory I 2 Credits (4 Contact Hours)
Experiments to illustrate current methods used in biochemical research. Preq: Consent of instructor.
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BCHM 6340 - General Biochemistry Laboratory II 2 Credits (4 Contact Hours)
Continuation of BCHM 6330 . Preq: Consent of instructor.
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BCHM 6360 - Molecular Biology: Genes to Proteins 3 Credits (3 Contact Hours)
Examines how nucleic acids and proteins are synthesized in prokaryotic and eukaryotic cells. Designed for students interested in biochemistry, cell biology, molecular biology, and cell physiology. Preq: Consent of instructor.
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BCHM (GEN) 6400 - Bioinformatics 3 Credits (3 Contact Hours)
Theory and application of computational technology to analysis of the genome, transcriptome, and proteome. May also be offered as GEN 6400 . Preq: Consent of instructor.
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BCHM 6430 - Molecular Basis of Disease 3 Credits (3 Contact Hours)
Topics in heritable human metabolic disorders, including clinical features and newborn screening, genetic testing, the biochemical basis, and treatment. Preq: Consent of instructor.
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BCHM (GEN) 8050 - Issues in Research 3 Credits (3 Contact Hours)
Scientific writing, oral presentations and critical evaluation of them; legal and ethical issues associated with modern biochemical research. Science job hunting, time management and creativity for professional scientists are treated. May also be offered as GEN 8050 . Preq: Enrollment in Biochemistry and Molecular Biology program.
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BCHM (GEN) 8100 - Principles of Molecular Biology 4 Credits (4 Contact Hours)
Introduction to the principles and techniques used to analyze prokaryotic and eukaryotic gene and genome structure, regulation of transcription initiation, regulation of protein synthesis and protein function. May also be offered as GEN 8100 . Preq: Consent of instructor.
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BCHM 8140 - Advanced Biochemistry 4 Credits (4 Contact Hours)
Contemporary topics of functional and cellular aspects in biochemistry with particular focus on new observations, emerging ideas and important techniques. Preq: Consent of instructor.
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BCHM (GEN) 8200 - Genomics and Proteomics 3 Credits (3 Contact Hours)
Genomes, transcriptomes and proteomes of a variety of organisms are studied along with the technology used to obtain them. Bioinformatics tools and access to this information are developed, and the significance of this information for the life sciences is made clear. May also be offered as GEN 8200 . Preq: BCHM 8140 or GEN 8140 .
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BCHM (GEN) 8250 - Seminar I 1 Credits (1 Contact Hours)
Special topics and original research in genetics reviewed by students, faculty and invited lecturers. May be repeated for credit. May also be offered as GEN 8250 . Preq: Enrollment in Biochemistry and Molecular Biology program.
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BCHM (GEN) 8510 - Seminar II 1 Credits (1 Contact Hours)
Investigation of current topics in biochemistry. May be repeated for a maximum of ten credits. To be taken Pass/No Pass only. May also be offered as GEN 8510 . Preq: Enrollment in Biochemistry and Molecular Biology program or the Genetics program.
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BCHM 8900 - Special Topics in Biochemistry 1-6 Credits (1-6 Contact Hours)
Group discussions of recent developments in biochemical research. May be repeated for a maximum of six credits, but only if different topics are covered. Preq: Consent of instructor.
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BCHM 8910 - Master’s Thesis Research 1-12 Credits (1-12 Contact Hours)
Master’s Thesis Research
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BCHM 9910 - Doctoral Dissertation Research 1-12 Credits (1-12 Contact Hours)
Doctoral Dissertation Research
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Bioengineering |
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BIOE 6120 - Orthopaedic Engineering and Pathology 3 Credits (3 Contact Hours)
Interdisciplinary study of clinical orthopaedic cases (bone growth, bone remodeling, osteoarthritis, implant fixation and joint replacements); biomechanical, biomaterials, tribology and clinical diagnosis of failed implants (total joint replacements, fracture fixation and spinal instrumentation); basic concepts of orthopaedic pathology for engineers. Preq: BIOE 3020 and BIOE 3200. Preq or concurrent enrollment: BIOL 3150; or consent of instructor.
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BIOE 6150 - Research Principles and Concepts 1 Credits (1 Contact Hours)
Introduces seniors and graduate students to principles and practices of scientific research. Topics include developing scientific concepts, developing projects, pursuing research, collaborating in multidisciplinary teams, patenting and publishing technical and scientific information, and reviewing professional and ethical standards of performance.
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BIOE 6200 - Sports Engineering 3 Credits (3 Contact Hours)
Study of engineering principles involved in sports: body systems in human motion, analysis of gait, basic performance patterns in athletic movements, performance improvements, design of sports equipment. Preq: BIOE 3020 and BIOE 3200.
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BIOE 6230 - Cardiovascular Engineering and Pathology 3 Credits (3 Contact Hours)
Medical and bioengineering aspects of artificial cardiovascular and vascular devices; physiology and pathological aspects of patients with need for such devices; diagnostic techniques and surgical management of diseases and pathology; design aspects of current devices and selection; state of the art in experiments and human clinical trials. Preq: BIOE 3020 and BIOL 3150; and either BIOE 3200 or BIOE 3210.
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BIOE 6310 - Medical Imaging 3 Credits (2 Contact Hours)
Introduction to the history, physics, and basis of medical imaging devices; including X-ray, Computed Tomography, Magnetic Resonance Imaging, and Ultrasound. Students will understand imaging from both an engineering and clinical prospective. Students will have the opportunity to work with real medical-images, to understand the trade-offs between modalities. Preq: MATH 2080; and one of ECE 2020 or ECE 2070. Preq or concurrent enrollment: BIOE 3700. Coreq: BIOE 6311 .
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BIOE 6311 - Medical Imaging Laboratory 0 Credits (2 Contact Hours)
Non-credit laboratory to accompany BIOE 6310 . Coreq: BIOE 6310 .
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BIOE 6350 - Computer Modeling of Multiphysics Problems 3 Credits (3 Contact Hours)
This course will introduce students to a holistic way to deal with complicated engineering problems using a computer modeling approach. For example, a real-world problem governed by combined mechanical, electrical, thermal, electrochemical and mass-transport phenomena will be dealt with in an integrated and multidisciplinary way rather than the conventional piece-wise single-discipline way. Preq: MATH 2080.
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BIOE 6400 - Biopharmaceutical Engineering 3 Credits (3 Contact Hours)
This course examines the design principles necessary to use bacteria, fungi, and mammalian cells in bioengineering applications, including molecular techniques, fermentation, process scale-up, purification processes, and FDA regulations. The production of biopharmaceuticals derived from recombinant systems, including uses in medical systems, in emphasized. Preq: BCHM 3050.
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BIOE 6710 - Biophotonics 3 Credits (3 Contact Hours)
Biophotonics is an interdisciplinary subject of applying photonics to study biological samples from individual cells to the entire body. Introduces fundamental and frontier topics in optical imaging aspects of biophotonics for senior-level undergraduates and graduate students to gain the ability to solve bioimaging-related biomedical problems. Preq: MATH 2080; and PHYS 2210; and either ECE 2070 or ECE 3200; or consent of instructor.
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BIOE 6820 - Biomaterial Implantology 3 Credits (2 Contact Hours)
Provides training in the planning and conduct of experimental surgery, including laws and regulations; institutional requirements; selection of animal models; ethical considerations of animal research; preparation of animals for surgery; general and special surgical techniques; aseptic surgical techniques; and basic and applied instrumentation. Preq: Junior standing in Bioengineering. Coreq: BIOE 6821 .
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BIOE 6821 - Biomaterial Implantology Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany BIOE 6820 . Coreq: BIOE 6820 .
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BIOE 8000 - Seminar in Bioengineering Research 1 Credits (2 Contact Hours)
Original research in bioengineering; weekly one-hour seminar associated with weekly recitation covering seminar preparation, presentation, professional writing, bioengineering ethics and related topics. To be taken Pass/No Pass only.
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BIOE 8010 - Biomaterials 3 Credits (3 Contact Hours)
Structure and properties of the main classes of materials used in artificial organs and surgical implants; metals, ceramics, polymers, composites and materials of biological origin; mechanical properties, corrosion and design. Preq: Consent of instructor.
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BIOE 8020 - Compatibility of Biomaterials 3 Credits (1 Contact Hours)
Determining compatibility of biomaterials with the physiological environment; optical microscopy, microradiography and ultraviolet fluorescence; normal histology of tissues, basic pathological reactions and tissue reactions to materials. Coreq: BIOE 8021 .
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BIOE 8021 - Compatibility of Biomaterials Laboratory 0 Credits (6 Contact Hours)
Non-credit laboratory to accompany BIOE 8020 . Coreq: BIOE 8020 .
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BIOE 8030 - Polymeric Biomaterials 3 Credits (3 Contact Hours)
Interplay of physicochemical properties of polymeric materials and the design of biomedical devices and their in vitro and in vivo performance; critical manufacturing aspects of selected augmentation and prosthetic devices for soft and hard tissues; analysis of case studies and reports on recent research findings. Preq: Consent of instructor.
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BIOE 8070 - Nanotechnology and Biomaterials 3 Credits (3 Contact Hours)
The emerging field of nanotechnology and its relation to solving bioengineering and health-related problems is treated. Also considers the promise of nanotechnology in the creation and utilization of materials and devices at the level of atoms and molecules. New scientific approaches, research tools, clinical tools, and devices are presented.
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BIOE 8110 - Sterilization and Cleaning Engineering for Medical Devices 3 Credits (2 Contact Hours)
Detailed overview of sterilization, cleaning and packaging requirements for reprocessing medical devices. Emphasizes evaluation methods for materials analysis, biocompatibility, and sterilization/cleaning methods in manufacturing and healthcare sectors. Compliance with industry and government regulations are addressed, including packaging processes, container types, and equipment design and processing for sterilization and cleaning. Coreq: BIOE 8111 .
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BIOE 8111 - Sterilization and Cleaning Engineering for Medical Devices Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany BIOE 8110 . Coreq: BIOE 8110 .
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BIOE 8130 - Industrial Bioengineering 3 Credits (3 Contact Hours)
A broad-based understanding of industry-related functions; knowledge base to allow a bioengineering graduate to quickly adapt to an industrial career in medical device research and development, and understand the additional roles and interplay between quality, sales, product development methodology, and regulatory.
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BIOE 8140 - Medical Device Commercialization 3 Credits (3 Contact Hours)
Overview of design control and regulations for medical device reprocessing and their practical application in the scope of project management and commercialization. Introduction to a cross-disciplinary approach for launching and marketing a new device, including device lifecycle management and intellectual property laws relative to the medical device reprocessing industry. Preq: Consent of instructor.
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BIOE 8150 - Design, Manufacturing and Validation Methods for Reusable Medical Devices 3 Credits (3 Contact Hours)
Overview of design theories, methods and best practices governing the medical device reprocessing industry. Materials, fabrication processes and manufacturing techniques with an emphasis on remanufacturing, reprocessing and sustainability. Knowledge and skills needed to comply with process verification and validation requirements for Quality System Regulations with emphasis on a reprocessing approach. Preq: BIOE 8110 or consent of instructor.
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BIOE 8160 - Bioengineering Career Professional Development 3 Credits (3 Contact Hours)
Addresses problems bioengineering graduate students may encounter in their professional careers. Guest speakers and faculty present lectures and demonstrations on information pertinent to research career development, grantsmanship, university-industry relationships, intellectual property, research lab management and budget development, biomedical engineering ethics, regulatory affairs and clinical trials.
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BIOE 8200 - Structural Biomechanics 3 Credits (3 Contact Hours)
Mechanical functions of the human body treated as an engineering structure and the devices used to assist and supplement these functions; movement of the musculoskeletal system; locomotion; gait; prehension; lifting; function of artificial limbs; orthopedic prostheses and braces; effect of vibration and impact on the body; mathematical and other models of the body. Preq: Consent of instructor.
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BIOE 8240 - Cellular and Molecular Analysis in Tissue Engineering 4 Credits (3 Contact Hours)
Describes the molecular basis for cell regulation by extracellular stimuli including growth factors, matrix and force. Also describes theoretical and laboratory instruction in research methods used to analyze cellular signaling and functional response in the design and evaluation of tissue engineering constructs. Preq: BIOE 8490 or consent of instructor. Coreq: BIOE 8241 .
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BIOE 8241 - Cellular and Molecular Analysis in Tissue Engineering Laboratory 0 Credits (3 Contact Hours)
Non-credit laboratory to accompany BIOE 8240 . Coreq: BIOE 8240 .
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BIOE 8250 - Cardiac Pathophysiology and Pharmacology 3 Credits (3 Contact Hours)
Advanced structural and functional aspects of the cardiovascular system, including cardiac physiology and cellular electromechanical physiology, pathological processes and congenital defects of the cardiovascular system as depicted in an invasive cardiovascular laboratory. Standard cardiovascular pharmacologic agents are discussed as they relate to the electrophysiology patient. Preq: BIOE 3700 and BIOL 3150 and consent of instructor.
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BIOE 8260 - Cardiac Electrophysiology Laboratory 3 Credits (9 Contact Hours)
Introduction to procedure room preparation, aseptic technique, regulatory compliance, patient identification and procedural consent; medical record and laboratory results review; and appropriate conduct with patients and staff. Instruction on identification and use of standard surgical instruments, cardiac catheter placement and potential complications. Calibration and assessment of intracardiac and intra-arterial pressure waveforms. Preq or concurrent enrollment: BIOE 8250 ; or consent of instructor.
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BIOE 8270 - Cardiac Electrophysiology and Arrhythmias 3 Credits (3 Contact Hours)
Recording and interpreting electrocardiograms (ECG). Identification and measurement of ECG waveforms, parameters, recording errors and artifacts. Use of standard ECGs, Holter and Event monitors, implantable loop recorders, stress tests, signal averaged, ECGs, T-wave alternans testing. Mechanisms of arrhythmia formation and methods of pharmacologic and interventional treatments. Preq or concurrent enrollment: BIOE 8260 ; or consent of instructor.
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BIOE 8280 - Implantable Cardiac Devices 3 Credits (1 Contact Hours)
Design of clinically used pacemakers, defibrillators, and cardiac resynchronization devices. Covers modes and basic timing cycles of pacemakers; testing of leads for sensing, impedances, and capture thresholds; pacemaker malfunction assessment; programming of antitachycardia pacing and defibrillation threshold testing for defibrillators; and device surgical implantation and explanation and methods of lead extraction. Preq: BIOE 8260 or consent of instructor. Coreq: BIOE 8281 .
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BIOE 8281 - Implantable Cardiac Devices Laboratory 0 Credits (6 Contact Hours)
Non-credit laboratory to accompany BIOE 8280 . Coreq: BIOE 8280 .
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BIOE 8290 - Interventional Electrophysiology Procedures 3 Credits (1 Contact Hours)
Interventional electrophysiology procedures, including baseline interval measurements, pulse stimulator control for diagnostic information, conduction system and refractory periods assessment. Supraventricular and ventricular tachyarrhythmias assessment, post-pacing and pacing protocols; radiofrequency ablation and complications; radiofrequency generator and irrigated tip ablation systems and transseptal punctures. Preq: BIOE 8260 and BIOE 8270 , or consent of instructor. Coreq: BIOE 8291 .
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BIOE 8291 - Interventional Electrophysiology Procedures Laboratory 0 Credits (6 Contact Hours)
Non-credit laboratory to accompany BIOE 8290 . Coreq: BIOE 8290 .
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BIOE 8300 - Interventional Electrophysiology Imaging 2 Credits (6 Contact Hours)
Methods of imaging utilized during electrophysiologic procedures. Three-dimensional CT images of the heart editing; echocardiographic planer images for three-dimensional cardiac chambers; standard radiographic imaging techniques, including rotational angiography; 3-D electroanatomic maps for arrhythmia assessment and ablative treatment. Preq or concurrent enrollment: BIOE 8290 ; or consent of instructor.
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BIOE 8310 - Advanced Electrophysiology Procedures 2 Credits (6 Contact Hours)
Electrophysiologic procedures and methods to treat atrial fibrillation and ventricular tachycardia; recording, imaging, mapping and ablative methods; and setup and maintenance of robotic mapping and ablation. Preq: BIOE 8280 and BIOE 8290 ; or consent of instructor.
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BIOE 8320 - Advanced Electrophysiology Problem Solving 2 Credits (6 Contact Hours)
Trouble shooting of electrical noise, grounding problems, fractured cables, insulation breaks, computer and imaging errors. Covers treatment of complications from procedures such as respiratory failure, cardiac tamponade, cardiac arrest, stroke, loss of pacing capture, use of transcutaneous pacing, external defibrillation, inappropriate shocks, placement of pericardial drains, chest tubes, and hematoma expansion. Preq or concurrent enrollment: BIOE 8310 ; or consent of instructor.
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BIOE 8410 - Drug Delivery 3 Credits (3 Contact Hours)
Comprehensive principles of drug design, development and delivery in the context of creating biomaterial-based prodrugs and applying pharmaceutical therapies in tissue engineering/regenerative medicine. The relationship between drug physico-chemical properties and pharmacokinetics/pharmacodynamics and drug delivery systems to improve therapeutic efficiency and reduce toxicity through targeting and controlled release is covered. Students are expected to have completed undergraduate courses in organic chemistry and cell biology before enrolling in this course.
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BIOE 8460 - Biomedical Basis for Engineered Replacement 3 Credits (3 Contact Hours)
Form and function of human organs, major systems and examples of engineering repair and replacement methods are presented in light of pathological or traumatic organ malfunction. Core course for all Bioengineering graduate students, taken preferably during their first fall semester.
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BIOE 8470 - Transport Processes in Bioengineering 4 Credits (4 Contact Hours)
Mathematical modeling of blood flow through capillaries and solute transfer from capillaries to tissues by diffusion and convection, pharmacokinetic analysis of drug adsorption, transport and elimination routes in body, and analysis of the design and performance of extracorporeal devices for organ replacement, including hemodialysis, blood oxygenation and immobilized enzyme reactors. Students are expected to have completed coursework in undergraduate-level engineering math, including calculus through differential equations, before enrolling in this course.
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BIOE 8480 - Cellular Interactions with Biomaterials 4 Credits (2 Contact Hours)
Cell biological concepts and issues relevant to cell-biomaterial interactions; methods for studying cell structure and function including basic cell culture techniques and in vitro biocompatibility analyses; biomaterial physio-chemical properties which influence cellular interactions; interactions between implant materials and host tissues at the cellular and molecular level; overview of tissue engineering. Coreq: BIOE 8481 .
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BIOE 8481 - Cellular Interactions with Biomaterials Laboratory 0 Credits (2 Contact Hours)
Non-credit laboratory to accompany BIOE 8480 . Coreq: BIOE 8480 .
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BIOE 8490 - Tissue Engineering 3 Credits (3 Contact Hours)
Principles and practices of bioartificial organ and tissue development; cellular/material interaction and translation of information from two-dimensional surfaces to three-dimensional scaffolds; selection and processing of biomaterials to form tissue scaffolds; analysis of tissue engineered devices, standards and regulation. Preq: BIOE 8010 and BIOE 8460 .
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BIOE 8500 - Selected Topics in Biomedical Engineering 1-4 Credits (1-4 Contact Hours)
Advanced topics in bioengineering intended to develop in-depth areas of particular student interest. Credit may be earned for more than one semester.
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BIOE 8510 - Mentoring Undergraduate Research Teams 2 Credits (2 Contact Hours)
Provides students with training and practical experience for managing and leading teams engaged in scientific research and medical device design/development. Students receive training from a faculty instructor while mentoring teams of undergraduate researchers. Preq: Consent of instructor.
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BIOE 8600 - Biomedical Engineering Device Design Innovation 3 Credits (3 Contact Hours)
In-depth review of regulatory, engineering, manufacturing and sterilization considerations required for the design and commercial development of medical devices. Preq: Consent of instructor.
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BIOE 8610 - Biomedical Engineering Product Translation 3 Credits (1 Contact Hours)
Graduate student teams work to iteratively design and prototype a medical device based on an identified clinical need and ultimately test their designs according to U.S. Food and Drug Administration (FDA) guidance documents and consensus standards prior to authoring a pre-market submission to the FDA for their device. Preq: BIOE 8600 . Coreq: BIOE 8611 .
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